Hundreds of leads are summarized in the histogram at http://morse.kiwi.nz/kingsley/lib/exe/fetch.php?cache=&media...
The May 22 paper by Hashizume et al suggests glycine[1].
I took the liberty of data mining my big spread sheet of life span experiments[2] for it.
It turns out that it was reported in 2011 that adding glycine to the diet of lab animals let them live 28% longer[3].
A ton of other cool experiments have already been done[2].
References
[1] Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects, Nature, May 22, 2015, Hashizume et al. http://www.nature.com/srep/2015/150522/srep10434/full/srep10...
[2] The World's Biggest Spread Sheet of Life Span Experiments http://morse.kiwi.nz/kingsley/doku.php?id=science:kingsleys_... http://morse.kiwi.nz/kingsley/lib/exe/fetch.php?media=:scien...
[3] The FASEB Journal. 2011;25:528.2, Dietary glycine supplementation mimics lifespan extension by dietary methionine restriction in Fisher 344 rats, Brind et al. http://www.fasebj.org/cgi/content/meeting_abstract/25/1_Meet...
Hundreds of leads are summarized in the histogram at http://morse.kiwi.nz/kingsley/lib/exe/fetch.php?cache=&media...
The May 22 paper by Hashizume et al suggests glycine[1].
I took the liberty of data mining my big spread sheet of life span experiments[2] for it.
It turns out that it was reported in 2011 that adding glycine to the diet of lab animals let them live 28% longer[3].
A ton of other cool experiments have already been done[2].
References
[1] Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects, Nature, May 22, 2015, Hashizume et al. http://www.nature.com/srep/2015/150522/srep10434/full/srep10...
[2] The World's Biggest Spread Sheet of Life Span Experiments http://morse.kiwi.nz/kingsley/doku.php?id=science:kingsleys_... http://morse.kiwi.nz/kingsley/lib/exe/fetch.php?media=:scien...
[3] The FASEB Journal. 2011;25:528.2, Dietary glycine supplementation mimics lifespan extension by dietary methionine restriction in Fisher 344 rats, Brind et al. http://www.fasebj.org/cgi/content/meeting_abstract/25/1_Meet...