Spain is strong as a Club League, not so much as a National Team. Germany is important to the World Cup, but it's not enough... Remember that in every World Cup, some "important" countries are left out in the Qualifiers.
To really hit the tournament, you would need the support from several historical and relevant members in each Association. As an example:
USA, Mexico in Concacaf; Argentina and Brasil in Conmebol; Italy, Germany, France and England, Spain (mainly for their leagues) in UEFA.
Let's say Germany 'secedes' from FIFA. I know for a fact that if Holland (I'm Dutch, but same thing goes for England) were to win the next World Cup in the absence of Germany, it wouldn't be taken seriously. I'd say most Dutch football fans would rather not win it at all in the absence of Germany. If they didn't qualify, well that's a whole different story, then they obviously weren't good enough to start with.
To really hit the tournament, you would need the support from several historical and relevant members in each Association. As an example: USA, Mexico in Concacaf; Argentina and Brasil in Conmebol; Italy, Germany, France and England, Spain (mainly for their leagues) in UEFA.