The fumes especially are a good point, hadn't thought of that. SLS is also possible with plastic, though, in which case I guess the fumes are comparable to those produced by an extrusion printer.
Well, almost. The SLS uses very fine grains as a base material, an extrusion printer uses a filament. The grains will vaporize much easier than filament but there is definitely a concentration of unhealthy particles in the air around an extrusion printer and I would not operate one without at least basic precautions (fume hood or something similar).
