Yes, it is an extremely unsettling feeling. Head trauma can also cause it. This is something I experienced recently. For about a week I was disconnected with my body and reality, a feeling like my soul had lost touch with the world, and it is not something I ever want to experience again. The anxiety this feeling causes is almost unbearable. It's difficult to explain, but if anyone has experienced ketamine, I would relate it to that. Head injuries are weird, I am still recovering 7 weeks later, but I am recovering well.