My product's client base is 9% IE7 and 60% IE8. Mainly hospitals and .gov agencies use our system. It's getting really hard to even test with those browsers let alone find frameworks that will work for our client base and we can't even force them off, because "IT says we can't install anything because it's insecure." AH!

It's pretty bad. We once got a ticket to make sure our app works with "ALL BROWSERS" because it was broken in IE6. That ticket was 6 months ago. The users are out there.