It won't because the bandwidth of TB2 cannot transfer the amount of data needed for a 5K display. The new Retina iMacs can get away with it because it can interface with the graphics output directly.
Displayport (and HDMI) have a 2 bit ECC overhead for every 8 bits transmitted, so effective bandwidth of DP 1.2 is 17.28 Gbit/s. Additionally, the timing adds additional overhead, so the required bandwidth is actually 22.18 Gbit/s for 24bpp 60Hz 5120x2880
I don't know the actual answer, but it may be that the display actually expects 32bpp, in which case it would be over the limit by a considerable amount.
Thanks for the clarification. fwiw, I knew that alpha wasn't necessary, but vaguely remembered that DisplayPort might support displays that expected the entire 32 bit word to be sent. Looking at the specs, I don't see that. But it does show that DisplayPort supports 16 bits per component, or 48bpp.