Activate Developer Tools in the preferences of Safari. This gives you a Developer menu in the toolbar. When a site refuses to play video on your Mac because it needs Flash, you tell Safari to pretend it's an iPad. The site invariably serves you the video you wanted, without Flash.
I read this advice previously on HN, and it worked for a while. Then Google changed something, and it stopped working. I don't know, maybe I was screwing up. Or maybe it's just easier for Google to roll ads ahead of the video when it's in Flash. Or maybe Google wants me to download Chrome, which has a built in Flash player. Not gonna do that until it supports NoScript. YMMV, obviously.