"and the mechanism is likely keyed off of testosterone in general rather than mouse smells in particular, which seems reasonable."
Yes, this is what Figure 1c and 1d of the paper demonstrate. (To be precise, not testosterone, but adrostenone, androstadienone, and 3M2H).
"My head isn't going to explode if this is established by further experiment. But it's suspicious to me."
Supplementary Fig. 1 and Supplementary Fig. 3 describe replications performed in two other laboratories, one at the University of Alabama, Birmingham, and the other at another laboratory at McGill.
Look, I'm all for scientific skepticism, and it's true that there's a lot of low-powered stuff out there. However, papers are best evaluated on what they actually say (which, incidentally, is why open-access/archiving is important), rather than on a filtered impression of what a press release says. If you'd like a copy of the paper, let me know, I'd be happy to send you a pdf.
Yes, this is what Figure 1c and 1d of the paper demonstrate. (To be precise, not testosterone, but adrostenone, androstadienone, and 3M2H).
"My head isn't going to explode if this is established by further experiment. But it's suspicious to me."
Supplementary Fig. 1 and Supplementary Fig. 3 describe replications performed in two other laboratories, one at the University of Alabama, Birmingham, and the other at another laboratory at McGill.
Look, I'm all for scientific skepticism, and it's true that there's a lot of low-powered stuff out there. However, papers are best evaluated on what they actually say (which, incidentally, is why open-access/archiving is important), rather than on a filtered impression of what a press release says. If you'd like a copy of the paper, let me know, I'd be happy to send you a pdf.