My only issue with the CSS from this is on .column it specifies the display as inline and then with another class sets the width. I can't remember right now but I had particular issues when trying to do the same thing a year or so ago and it turns out that its not W3 spec. Without the inner p tag creating a display block element the grid breaks down. In short display inline elements cannot by themselves have width assigned to them.
I've been using the 960.gs for a while now and really find it efficient. At first I was critical of such systems but the ability to reuse css classes is great and it's a nice having a starting point for new site layouts.
I suppose this has its place for simple fixed width designs, but when you need something more flexible I love YUI grids (which they seem to be responding to with this simpler grids css)
http://www.w3.org/TR/2003/WD-CSS21-20030915/visuren.html#inl...