It's interesting that Facebook and Amazon have a terrible experience for blind users, considering their wealth of resources. I imagine it is common knowledge among blind users to expect the mobile site to perform better, if the desktop site is sucky.
I have no issue using the main amazon site with Jaws as a screen reader. I'm sure part of that is that I've been using Jaws for close to 20 years but it doesn't appear this guy used navigation by headers which makes amazon quite usable.