I find that for simple apps, a lot of the hybrid frameworks can get you 95% of the way there in terms of user experience. And if you don't plan on using any native UI stuff, then you might be fine. But then you'll run into some weird CSS issue or something that breaks your heart (and your design).

I tried AppGyver's Steroids offering (which is based on Cordova) and was quite impressed, but ultimately decided it wasn't quite up to snuff, which sucked because I really wanted it to be.