All of those examples except D.C.-Baltimore are from a major city to a suburb or minor city. San Jose is actually a larger city than San Francisco and along the route you'll find half a dozen cities on the scale of Wilmington or Trenton.
San Jose is a bit of a paradox; it's a larger, sprawling city, but it's basically a giant suburb to some extent. It has never been a place for startups, and even most of its resident tech giants are in office parks in suburban areas away from downtown.