Hey, long-time iOS dev here. Interface Builder is emphatically a beginner's friend. For "major league" stuff it is wholeheartedly the enemy. Avoid Storyboards like the plague. It's merge nightmare city when in teams, and a big enough app will suffer under the complexity required. It's simply not worth the pain.
With DCIntrospect (https://github.com/domesticcatsoftware/DCIntrospect), positioning in code actually becomes easier than nibs. You can print out the view properties, tweak positioning, then once it looks right you can get the values you need to tweak your code.
Additionally, getting to know UIAppearance and adding categories to UIColor and UIFont that return your app's standard fonts let you create a styleable application with consistent typography and color palette.
With DCIntrospect (https://github.com/domesticcatsoftware/DCIntrospect), positioning in code actually becomes easier than nibs. You can print out the view properties, tweak positioning, then once it looks right you can get the values you need to tweak your code.
Additionally, getting to know UIAppearance and adding categories to UIColor and UIFont that return your app's standard fonts let you create a styleable application with consistent typography and color palette.