1 in 50 seems... very, very optimistic. On top of that, the investment is higher than the lottery. The lottery costs you $1. This costs you ~$10-20k in salary, and possibly more in lost opportunities and time you would've had elsewhere.
In short, 13% of VC-backed startups exit for over $10M, 5% exit for over $50M, and 2% exit for over $100M, which is what I'd call significant.
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Besides, there are a lot of startup opportunities that pay market, so you aren't "investing" anything in the equity, it's a bonus over what you'd get paid elsewhere.
