You're not the first criticising this about my library. I used adapters in another lib of mine (http://www.opentip.org) and it worked great, but the work involved in testing all browsers is not comparable to just using jQuery (especially when working with events). But it is definitely on my todo list (https://github.com/enyo/dropzone/issues/39).

EDIT: PS: I also chose jQuery over any other lib just because it's the most wide spread. Personally I have worked with Ender, Component, RequireJS and don't use jQuery in all my projects.