Correction: 350,000 years being riddled with parasites, fending off wild animal attacks, and avoiding being eaten alive by cannibals when your tribe runs out of food.
Parasites are my main go-to when I meet someone complaining about the modern world. In the history of multicellular organisms on earth, only (some) humans—and only in the last ~100 years—have had the luxury of not being completely infested with parasites.
Even now we have more parasites than we probably know or care to admit.
This was / is likely a factor in the "kernel of truth" with the whole "deworming tablets cure covid-19" thing, the chances of survival of people in certain areas infected with the virus increased if they were administered deworming medication because they also had a parasitic infection.
Yes my friend took ivermectin recently because he grew up in he Virgin Islands and realized he had likely been harboring parasites his whole adult life. I don’t know if it is placebo but his eating habits changed significantly after his dose
The fact that low-grade parasite-infections dampen autoimmune diseases isn't that big of a win. Presumably our immune system is as aggressive as it is in part due to the parasite-load our ancestors were exposed to.