Interesting! Depending on your definition, "automated invention" has been a thing since at least the 1990's. An early success was the evolved antenna [1].
4F-* are mainly research chemicals (still?), still being sold widely, especially where there is not a blanket ban on them.
I remember 3-FPM, that was what I imagined stimulants should be doing. It did everything just right. I got it back when it was legal. Any other stimulants come nowhere as close, maybe similar ones, but 4FA or whatever is for example, mostly euphoric, which is not what I want.
1. https://en.wikipedia.org/wiki/Evolved_antenna