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> If Ozempic is so great then how come our bodies don't just produce more GLP-1?

We don't know. But one early signal is that you lose an atypical combination of muscle mass and not just fat, which is not a good evolutionary adaptation if you are an endurance hunter.

https://healthcare.utah.edu/newsroom/news/2025/08/new-study-...



Muscle-mass loss is normal on any weight-losing diet, and the link says it is actually less than expected…




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