FedEx'ing baggage between home and a distant hotel is awesome. I haven't done it recently, so maybe with airline fees it is always cheaper. It used to be that you had to have a corporate account with enough discounts to make it cheaper than checked luggage.
Big hotels host lots of conferences, legal depositions, business shows, etc. They get a FedEx truck almost daily and don't blink if a package arrives addressed to you with "Guest checking in on XXXX date" appended to it. It happens all the time! And when you leave, you call the front desk and ask them to take a box to the loading dock for the next FedEx truck.
When I travel, I often stay in rentals that have laundry machines, because it’s so much easier just to pack light and do laundry every couple of days. I’m also not against packing light with the intention of going shopping if I need something. That’s how I get a lot of fun clothes!
Or I just don't bring anything that won't fit in my lap.