There are also enzymes and secondary metabolites relevant to plant health associated with microbiome and ecological chains in healthy soil that go beyond the regenerative macronutrient cycles. If you try to grow edible fruits you'll notice flavor loss as a result of hydroponic / synthetic methods.
Next door neighbor to this: I read someone who had a theory that dwarfed plants were also part of the nutrient and flavor reductions in modern grocery fare.
The model they presented was that the plant stores nutrients all year, and then when it fruits it dumps those nutrients into the fruit. With dwarfism we’ve reduced the plant size and kept the fruit size with the theory that more photosynthesis goes into the fruit. But there’s also a smaller reservoir for everything else that goes into the fruit.