They were doing genetic sequencing across a decade or so at this one hospital to document how the bacteria is evolving to develop resistance - and it currently has resistance to a wide number of drugs.
Sounds like it is highly prevalent in hospitals in lesser developed countries and has been slowly developing resistance but not widely studied, and this particular strain at this particular hospital seems to be further along the path.
WHO considers it a "critical priority antibiotic-resistant pathogen."
It's an opportunistic pathogen that mainly spreads in hospitals among people who are immunocompromised or otherwise ill. Symptoms vary wildly, because it can infect different organs and tissues, and can include pneumonia and meningitis.
No one mentioned pandemic. It's a health threat--if this thing gets into a hospital its very, very hard to get rid of. Most people prefer their hospitals as sterile as possible.
Its also something that can become a damocles swoard. Like its living in your intestines harmlessly, but if you have a ulcer or somebody in your house gets with a cut near your toilet - exitus.
A global health threat doesn't have to be a pandemic affecting otherwise healthy people to be a global health threat. In this case, the threat would presumably be that the same bacteria winds up in health care facilities elsewhere.
"A. baumannii can cause infections in blood, lungs, urinary tracts, and wounds. It typically causes these in healthcare settings, such as hospitals. Owing to its ability to resist antibiotic treatment, it has been listed by the World Health Organization (WHO) as a critical priority antibiotic-resistant pathogen."
Your body should be able to get rid of it by itself, but if it can't, the infection will grow and be fatal.
It's not just in Malaysia, but typically these cases are rare so it being widespread is worrisome. We have MRSA in North-America, but hospital processes eliminate most of the spread of bacteria through thorough cleaning.
It's not much to worry about if you're in a first-world country, but this may cause a lot of deaths in these countries, and force them to spend more on cleaning procedures.
> but hospital processes eliminate most of the spread of bacteria through thorough cleaning.
Not really. I worked at a hospital over a decade ago and I during an onboarding training session we were told that 1/8 patients will receive an infection as a result of their hospital stay.
TIL "Efflux pumps are protein machines that use energy to pump antibiotics and other small molecules that get into the bacterial cytoplasm and the periplasmic space out of the cell." They even have their own bilge pumps!
They were doing genetic sequencing across a decade or so at this one hospital to document how the bacteria is evolving to develop resistance - and it currently has resistance to a wide number of drugs.
Sounds like it is highly prevalent in hospitals in lesser developed countries and has been slowly developing resistance but not widely studied, and this particular strain at this particular hospital seems to be further along the path.
WHO considers it a "critical priority antibiotic-resistant pathogen."
Most hits on the subject in the news seem to be coming from tabloid-level organizations. This looked fairly sane: https://medicalxpress.com/news/2025-03-deadly-antibiotic-res...
A reminder to HNers, from another HNer:
https://news.ycombinator.com/item?id=10812804
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