Meanwhile larger cells massively benefit by speeding up those processes. So there exists lot of structures to group and or transport where different molecules are.
Similarly, organelles group related process together. So for example DNA related proteins are in a nucleus not inefficiently bouncing off the cell wall.
Which helps explain why mitochondria were so beneficial. Keeping a bunch of related machinery all tightly clustered together it makes more efficient use of each individual protein and can quickly replace anything that gets damaged. ATP however can diffuse through the cell just fine because so many processes use it that extra copies isn’t a major issue.
https://en.wikipedia.org/wiki/Golgi_apparatus
Similarly, organelles group related process together. So for example DNA related proteins are in a nucleus not inefficiently bouncing off the cell wall.
Which helps explain why mitochondria were so beneficial. Keeping a bunch of related machinery all tightly clustered together it makes more efficient use of each individual protein and can quickly replace anything that gets damaged. ATP however can diffuse through the cell just fine because so many processes use it that extra copies isn’t a major issue.