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It kick in slowly because standard administration is subcutaneous which isn't a very well vascularized tissue.

If you shoot up in your veins or into something more vascular you would have faster onset.




I participated in studies where they administered insulin and glucose intravenously. It is wild how they can reliably drop my blood sugar from high to low within a few minutes. Subcutaneously this takes me hours to do in a stable way.


Not only veins, inhalable insulin like Afreeza is also really quick. Unfortunately it only appears to be available in the US (and maybe Canada?), not Europe/Asia from what I last remember.


>If you shoot up in your veins

Which is a sure way to find yourself in a hypoglycemic coma.


Inhalable insulin (which is also very fast acting) iirc only allows a dose of 2 units. If your sugars are 400mg/dl (22ish mmol/l) one or two doses wouldn't put you into a coma if you knew your sensitivity. I'm pretty sure I've read up T1s talking about using it as such.


Sudden drops of the blood glucose level aren't good for health.




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