Rybelsus is harder on compliance (1-per-day, rather than 1-per-week), and the cost of the pill will always be high due to the excessive amount of peptide it wastes (700% more per day * 7-days = 7000% more wasteful than a single injection per week).
At some point it isn't "perfect Vs. good" it is "effective Vs. ineffective." Rybelsus is an ineffective medication. Even with the eye watering waste set out above, it is reported as being less effective as a GLP-1 too. There is no upside.
A pill GLP-1 is an absolute game-changer. We just aren't there yet.
Oral medications are much cheaper to manufacture than injectables. The Apis Bull is working on a drug combination that prevents the digestive system from burning up all the semaglutide.
At some point it isn't "perfect Vs. good" it is "effective Vs. ineffective." Rybelsus is an ineffective medication. Even with the eye watering waste set out above, it is reported as being less effective as a GLP-1 too. There is no upside.
A pill GLP-1 is an absolute game-changer. We just aren't there yet.