From my perspective, I don't think I ever see "the science" being decided based on a single crap paper, so it seems a bit of a skeptical straw man. Perhaps that's different in your country, state, city, county, continent, island. Perhaps that's true for a particular policy _area_ that you are invested in. In general, I find arguments on scarequotes "science" often overblown and just reinforcing existing biases.

How much 'policy' are you happy with that you've never checked to validate that it was properly replicated beforehand? How much of your skepticism is against "the science" on new policy you start with an initial dislike to...compared to policy that we consider as standard, are probably comfortable with, likely consider to be 'beneficial enough'...and yet haven't adequately scrutinized?