First of all, today I almost exclusively write all my LateX in overleaf, so a lot of pain of LateX distros is taken away. But the main thing was always good templates, so I found a collection of ML conference templates [0], that shows also that typst still has some issues with acutely reproducing existing styles. Also when having to submit sources, I guess cross compile to latex would be the only possibility (typically they accept Latex or sometimes MS Word)

[0] https://github.com/daskol/typst-templates