I personally lean to yes, but that's more about what people do with the results than the results themselves.

Here's an infamous example: https://en.wikipedia.org/wiki/Milgram_experiment#Validity

Honestly after reading that it seems impossible to really conclude anything...as it's just full of conflicting results...is that innately fraud? No but certainly careers/$ have been made from biased/agenda-driven interpretations which seems fraudulent.