One important note with mpox is that there are two distinct lineages of the virus at play: the outbreak in the US in 2022 was clade IIb, which seems to be difficult to spread - hence the “close physical contact” attribution. It also had a low observed CFR.
Clade I mpox is the current outbreak under discussion. It spreads far easier - most pathways are likely not sexual contact - and has an observed CFR 10x higher than IIb.
In other words: this is a very different virus than what we saw in 2022.
Clade I mpox is the current outbreak under discussion. It spreads far easier - most pathways are likely not sexual contact - and has an observed CFR 10x higher than IIb.
In other words: this is a very different virus than what we saw in 2022.
https://centerforhealthsecurity.org/sites/default/files/2024...