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> The key insight from Deming’s work is that at any given moment there is only and exactly ONE thing that should be optimized. Once you optimize that, there will be a new SINGLE thing that is now slowing down the entire system, and must be optimized.

Are you sure this is what Deming thought?

A complex system has many different things that can be locally optimized independently, here's an example:

1-DC picking optimization

2-Store inventory placement to align with demand to both increase sales and decrease costs of liquidating old inventory

Both of these have very significant impact on costs or revenue or both, and are largely independent. The process of picking in the DC is independent of the specific selection and inventory levels of skus in the stores.

Why would you not do both at the same time to get the benefits as quickly as possible?



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