Computers are like these magic devices to get us into potentially a fight or flight response with zero physical danger. People’s heart rates rise when they get an email from work. I can’t imagine its good for the health, mating these mental responses that are designed to go along with a physical response with just sedentary behavior instead. And doing it every day all your working life no less. What does this mean in terms of the underlying chemistry, are there neuortransmitters or hormones perhaps that aren’t getting processed or turned over by the physical response when they ought to? Maybe we should experiment running to the hills when we get an email from the boss and see if that changes things.