I assume this is a joke, but still... I have had Ghidra open in the background for a while (weeks), as I worked on some IoT projects for my cats. While I'm biased and I hold some unpopular opinions... I think not just me, but most people definitely would get offended if suddenly some game would refuse to start and/or ban online account.

Honestly, banning players because they have RE tools feels like a generally counter-productive idea. Best-case scenario is that it'll require an engineer who was actually going to RE game files to get another account, stalling them very briefly. Worst-case scenario is getting someone with technical skills and free time pissed off enough to actually start messing with the game (potentially, in a less respectful way than your average cheat developer might - looking for game-breaking exploits than just automating things or providing extra information to the player), even if they didn't mean to.