#21: Floating navbars are an abomination and make your site incredibly frustrating to read on a mobile device -- especially in landscape mode. At least put an X button on that thing.
The Subscribe by Email floater is what drove me batty, on a laptop. Stuff floating to the left not apparently docked to anything should move when I scroll!
Edit: it's a good list, though. Content > presentation, when it comes to actual reading material.
Also, if you're going to make a gimmicky website like that, at least have the decency to have something happen when I click on the door or the fan or whatever.