I started having some pain in my wrists and the top of my hands earlier this year.

I feel that switching my keyboard and mouse to Apple keyboard and mouse helped (especially the mouse), because of their low design, preventing my wrist from bending too much.

I also started practicing indoors climbing and this helped a lot for the flexibility and strength of my hands. I didn't feel any pain since then. You don't mention any physical activity in your blog but I'm convinced any sport involving the hands practiced regularly would help.