It's a very serious issue. I don't really know if there is any "one solution." I suspect that each project needs to set its own bar, and that any dependency that falls out of maintenance should be removed as quickly as possible (which was good practice, beforehand, but even more important, now).
[EDITED TO ADD]
I would also think about "scoring" the sensitivity of projects. Things like cryptography and low-level drivers would be highest-rated, while user-space chrome might not be as important.
It's a very serious issue. I don't really know if there is any "one solution." I suspect that each project needs to set its own bar, and that any dependency that falls out of maintenance should be removed as quickly as possible (which was good practice, beforehand, but even more important, now).
[EDITED TO ADD]
I would also think about "scoring" the sensitivity of projects. Things like cryptography and low-level drivers would be highest-rated, while user-space chrome might not be as important.