I'm aware that Atlantic and mid-American quakes are felt over a much wider area than Left-coast temblors, because of the more-intact, less-fractured, largely limestone and granitic foundation bedrock (as opposed to a largely fractured sedimentary basement along the Pacific seaboard). But is the actual shaking intensity greater? AFAIU that's mostly affected by factors such as ground liquifaction, total ground water, and the like, which tend to be fairly strongly localised in effect. E.g., you can find seismic hazard maps of the SF Bay Area which show high-risk regions, largely on fill, reclaimed marsh, and sand dunes (e.g., the Marina, Financial District, SOMA, Sunset and Richmond districts of San Francisco), as opposed to bedrock (Twin Peaks, Potrero Hill). The former all amplify ground movement, the latter tend to shake far less.
River bottom land and estuaries on the East Coast would similarly show higher seismic motion, but I'm not sure this carries over for the region as a whole.