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Oral Bacterium Migrates to Gut, Helps Colorectal Tumors Grow (genengnews.com)
19 points by bookofjoe on March 21, 2024 | hide | past | favorite | 14 comments


I wonder if the researchers considered directly inoculating the colorectal area. Is it necessary for this to pass through the upper gut?


Well what can I do about it?


IANAD, but I'd hypothesize that a healthy oral and gut bacterial biome heavily populated with the various good bacteria may serve the purpose of outcompeting undesirable bacteria and keeping them from growing past critical levels.


How do you do that? Is there anything actionable here?


This is not medical advice but for oral health you might try a system that attempts to both target bad bacterial and support good bacteria, such as one that incorporates xylitol gum as described and documented here by Ellie Phillips DDS (you don’t need to buy her xylitol gum of course): https://drellie.com/complete-mouth-care-system/

She also recommends a colon health probiotic and eating a healthy diet with a wide variety of plants and vegetables to improve the health of your saliva. She writes “Oral probiotics may seem a good idea, but many contain artificial sweeteners like Splenda, that can damage gut health… If you want an oral probiotic, I recommend Garden of Life Probiotic Smile lozenges, which contain strains of Streptococcus uberis KJ2, S.oralis KJ3 and S.rattus JH145, plus xylitol to feed probiotic bacteria.”

That said, as far as I know these recommendations were made for general oral health and not specifically about Fusobacterium nucleatum animalis C2.


Foods rich in good probiotic bacteria, such as strains of lactobacillus and bifidobacterium are a good place to start. Anything cultured or fermented is usually a good bet. There are also probiotic supplements, if you want a particular strain.

My guess would be that certain bacteria or strains are better than others at outcompeting the undesirable colonies, but you'd have to look for specific research to say which ones. In lieu of that, though, it's not hard to experiment with probiotics and see which, if any, have a noticeable positive impact on you.


Eating Plants


Brush & floss your teeth. Eat healthy. Sleep enough. Exercise.


Try your best not to swallow.


Put a UVC emitting light in your mouth for 5 minutes a day (please don’t)


why would that be a bad idea? to my uninformed brain that actually sounds interesting


With the modern short wavelength UVC LEDs, this is considered a promising new technique [1].

With longer wavelength UV, which is less absorbed by the cells, the light would penetrate deeper into the tissue and cause much more DNA damage. Still, broadband UV irradiation of throat, nose, and ear was a mainstream treatment in the USSR.

[1] https://www.nature.com/articles/s41598-023-49745-3


I remember Trump mentioned it in the beginning of corona as one of the discussed ideas and everyone laughed.


It kinda is laughable for a virus that lives in your lungs and blood.




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