Do you think he should be ashamed? Granted I may have overlooked something, but as far as I can tell it wasn’t an intentionally malicious act, it was a bit of a curious experiment. Seems rather inline with the HN values to me.
Shame is a spectrum. I don’t think he should flagellate himself until the end of time. I think that they should be a little bit embarrassed that they haven’t published what they believed the risk of the everything package was.
Upon rereading the article I can see that the word “unintended” is actually not Patrick’s but the author of the recap’s word.
Beyond that you seem to be ascribing benign intent. Reading it from the horses mouth [1] it doesn’t seems like they had any intent other than trying to find out if it could be done. In a world of worse is better creating the largest possible area of effect for your experiment seems to be a pretty easy way to amp up the consequences of your actions regardless of the risk.