Probably not. Plenty of toxic proteins have a published structure and are quite easy to grow in a lab (i.e. an undergraduate could do it). The problem with using proteins to do evil things is that they tend to have short half-lives, aren't easily transmissible, etc. There are some exceptions to this, of course, but there's far more practical ways to do evil things.

It seems implausible, and weighed against the probability of positive scientific discoveries made with the technology, it seems reasonable to proceed with caution.

Back when I was a maker i talked with the FBI and they said they knew it was OK/legal to work on viruses in your garage, "but just be sure to let us know if you see somebody doing something dangerous"