NewRelic's product screenshots look really nice, but 1) the hosted nature and 2) the price were turnoffs. We might revisit it at some point, though--there are a few features in there that would be awesome to have.
I think New Relic saves us money - the amount of optimizations we've done because of them is just crazy and by now would have saved us a couple servers and hardware upgrades at least.
Their sales dudes like startups, we were only lightly funded when we started using them - garth@newrelic could probably help you.
Had the same first impression, but compared to rolling your own solution it's still a very good ROI. And now I'm getting more and more servers and projects on it, because it's just so handy.
(Btw not connected in any way, jsut a very happy user that convinced enough companies to try them, that I think you would be a good match, too)