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Fish skin can heal other animals' eye injuries (scientificamerican.com)
123 points by LinuxBender on Oct 21, 2023 | hide | past | favorite | 43 comments



After laser treatment i can see perfectly, but the eye is permanently dry. It would be great if there was a fix for that.


I recommend seeing an ophthalmologist specializing in dry eye disease. They have tests for measuring tear breakup time (TBUT) and imaging equipment for viewing meibomian glands, which are specialized sebum glands that coat the eye surface in oil to form the tear film. Fish oil helps for that reason - Omega-3s improve sebum quality.

Personally I use preservative-free eye drops with hyaluronic acid [1] and they help out tremendously. I also use a heated dry eye mask, but I don't know if that helps with Lasik cases.

But it's best to try to treat it sooner rather than later. I ended up seeing my ophthalmologist in the first place because my cornea got damaged and infected, and he said that the eye dryness could have been a contributing factor.

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967738/


I recommend everyone an EU brand called Optase[1] for their suite of dry eye drops and related products! Best preservative free eyedrops I've tried (I've tried everything extensively) and its in a bottle! :D

They have a MGD Drop (red packaging) which is liquid/oily and an Intense drop (purple packaging) that is nice and thick.

You can find them rarely at retail pharmacies as they are still expanding in the US but you can order them on Amazon.


I got SMILE instead of LASIK for that exact reason (avoiding dry eye), and have perfect vision with moist eyes. Highly recommend avoiding LASIK if you qualify for newer procedures.


I had tPRK in June for a similar reason. Astounded with the outcome.


Fish oil helped me with that. (Coincidentally?)


Um, taking it orally or dropping it in your eye?

(I'm interested because my sister has just had eye surgery and while she is still adjusting to her new vision, she said something about potential dryness)


Just answering all the questions here:

Regular fish oil pills from Amazon or Walmart. My eye Dr recommended it. Just took a couple before bed.

For me the dry eyes started a year after the laser eye surgery. Really only night time was a problem.

The other thing that might have helped was installing a whole house humidifier.


>Regular fish oil pills

Do you mean cod liver oil capsules?


You could try that but just any fish oil capsules.


Thanks.


You just need Omega 3. I like the liquid bottled one that is flavored so it doesn't taste fishy.


Got it, thanks.


Seconded, the difference was stark. I take the generic gel caps.


Was it immediately after the procedure, or later on? It has been several years in my case.


have you used just a fish oil or some fish oil derivative ( high concentrate of omega3, or DHA, etc)?


I had terrible dry eye. I was treated for other medical problems which prescribed anastrozole and now I'm on TRT. My dry eye is now much better and I can feel it come back with the end of the TRT cycle. Back when I started these meds I wasn't expecting this and the only papers I found were about females. My doc didn't have a good explanation for the side effect.


TRT?



Yeah, that's what stopped me from getting LASIK. Even just constantly dry eyes would probably drive me insane


Oh no, that sounds very irritating. Do you have to use tear drops non-stop?


I should, but I dont. Just suffer, it is mild, but irritating.


Are you not worried about other long term damage from not having wet eyes?


Several years passed and nothing changed. Only one eye was operated, the other one is fine.


Tangent: I appreciate that the only glancing mention of the ethical weirdness in harvesting skin from one animal to heal surface injuries on other animals is in the beautifully crafted teaser graphic.

(To be clear, this is nothing like skinning beavers — it's tilapia after all, one of the most heavily consumed fish on the planet, skin and all. But the thought tickled the brain for a moment)


How is it any different from crushing vast numbers of fish up to feed other animals? Fishmeal is a common livestock feed.


> (To be clear, this is nothing like skinning beavers — it's tilapia after all, one of the most heavily consumed fish on the planet, skin and all. But the thought tickled the brain for a moment)


It's good because as I've learned from Stardew Valley tilapia is more than abundant.


I just bought a new bottle of Miracle Ointment™ (3.5 grams , $30) because, after 4 months of peace, my cornea decided to rip itself open again last night. Sigh. This is after 6 months of diligent application before bed every night, in order to finally heal a recurrent erosion stretching back 8ish years before.

Hopefully they'll get to us soon.


Has anyone ever brought up superficial keratectomy to you? Risk benefit discussion at least. Also, muro drops are otc and can help acutely


Can't afford it. And that's what I use (the ointment; the drops are worse than useless). They say 2 weeks or whatever, but you need months without a recurrence.


"Cell therapy that repairs cornea damage with patient's own stem cells achieves positive phase I trial results" (2023) https://news.ycombinator.com/item?id=37204123 :

> In this study, they found that only one brand (Bausch and Lomb IIRC) of contact lens worked well as a scaffold for the SC

From https://news.ycombinator.com/item?id=36912925 :

"Genetic and epigenetic regulators of retinal Müller glial cell reprogramming" (2023) https://www.sciencedirect.com/science/article/pii/S266737622...


Some guy will put videos of a patient getting lasik/*, records all the movements of the surgeon as input, shove it into a transformer model and there will be machines which do it 10x better than humans in 5 years. Might as well wait


I’ve never tried it but some people in the south (US) apply catfish slime to help heal wounds.


Can we change the title to "can be used to treat" instead of "can heal"? The current headline sounds almost like its happening in nature.


[flagged]


Brazil isn't developing?


Makes me sad to think about the 400 dogs they had to inflict eye injuries on to test this out.


“Mirza Melo, a veterinary ophthalmologist in northeastern Brazil's Ceará state”

Article says she treated them. I doubt they intentionally injured them.


Also, most cornea research in vivo is done on rabbits, not dogs.


Yeah... For clinical trials they need dogs that are healthy with consistent injuries. The only way to get that in the quantity is they need is to cause the injuries.

Where I went to college, there was a lab with 3,000 dogs in it. All of them were being used for scientific study. They couldn’t even let them outside because they didn’t know if the dogs would get sick (“contaminated”) and ruin the study. The dogs have been bred to have a heart defect. They were all euthanized at various stages to see how the defect was progressing. Many dogs did’t even have the defect but were put down and dissected anyway.


I'm not sure clinical trials were actually involved here, though.


Also makes me sad to think about a 80 billion (yes you read that right) animals killed each year for food but we don't like to talk about it because thats outside our overton window.

Not a vegan BTW.


This fish will be right peed off if people start using its skin to regrow hair




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