Sometimes it's not even "I use them not", sometimes it's "I need to use them because some program/whatever requires them" so there is no options.
And PrtScr on these keyboards replaces ContextMenu and I'm hardwired for a quarter of century to use it when I'm on the go without a mouse (hey, it's a laptop!). I lost my clipboard contents too many times so I had to figure it out, but it's ridiculous in the first place.
And overall it's like having a dildo in the driver seat of your car - you can choose to use it or not to, but still there should be no such thing in the driver seat of a car at all. /rant