whatever stack you're using, it probably doesn't have very stable support yet. afaik there is no SPDY for nginx, the apache module seems quite experimental, etc..
So, unless you have the chops to fix issues when they come up, you may want to wait a bit until things mature.
nginx support is in the works and I'm hoping we'll see something public in first half of this year. The apache module also got a lot of love recently, so definitely check it out.
Dev wise, probably the biggest hurdle for most people today is simply installing the latest SSL builds for NPN support (usually entails recompiling your favorite language against it as well).
So, unless you have the chops to fix issues when they come up, you may want to wait a bit until things mature.