Life in the deepest ocean requires considerable adaptation. For example, the proteins in your body would cease to function at that pressure, denatured to uselessness. The proteins the life has there are adapted to resist this. The organisms also have solutes, like trimethylamine, that help proteins maintain their structure. Many deep sea organisms are unpalatable because they contain such chemicals.

Go to high enough pressure and the very polymers of life begin to break. It becomes energetically favorable for proteins to be decomposed to individual amino acids, due to their now exposed charged ends assisting in compressing water.