The Sackler's were unscrupulous dope peddlers. The whole premise of Oxycontin was a lie: specifically that it lasted longer than it did; combined with actively pushing the medication for cases where it wasn't necessary helped set up the crisis.

That said, there will always be demand and that demand would be better served if not criminalized. These drugs should be made available for legal purchase but we need to find ways to incentivize minimizing the sale and consumption of such.

I fail to see the difference between letting an adult drink themselves to death vs doping themselves into oblivion. The former is both legal and acceptable whereas the latter is not; but they're effectively the same.