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> Plus, why should "GUI" get a pronunciation but "CLI" be neglected?

It's probably because the person who made the acronym or initialism had wanted it to be pronounced a certain way and chose a sequence of letters to achieve the desired result. Of course, the speakers of the letter-group will later decide when and how they will pronounce it!

  Acronym: a word formed from the initial letters
  or groups of letters of words in a set phrase or
  series of words and pronounced as a separate word [1]

  Initialism: a set of initials representing a name,
  organization, or the like, with each letter
  pronounced separately [2]
[1] https://www.dictionary.com/browse/acronym

[2] https://www.dictionary.com/browse/initialism



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