Unusable unreadable unnecessary complex abstractions in a language that doesn't need them. Also, extremely non-performant.
As you can see even in the blog post: straightforward readable code using built-in functionality is turned into 8-12 imports, a bunch of auxillary functions and multiple function calls that obscure the actual functionality. At 35 times speed penalty and 2 times memory penalty.
The library itself is fine. The problem I see is twisting JS/TS in to a language it is not.
JS simply does not lend itself to currying, data-last signatures, piping, and pattern matching like an ML family language does. And as you can tell by the Ramda typings, neither does the TS type system. [0]
You will forever fight an uphill battle against every single tutorial and piece of documentation and colleague when going down this path. I don't think the effort is worth it.
As much as I like these concepts, I'd be hesitant about adding them to the language. At what point does a language support too many paradigms?
In contrast, take the recently stage-3'd Iterator Helpers[0]. These build on top of the language by using methods that already exists in other parts. It feels natural and is more of the same.