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I'm impressed... "DNA Polymerase III"

DNA Polymerase III:

DNA polymerase III is an enzyme that is essential for DNA replication in bacteria.(McHenry, 1988) DNA polymerase III is a complex of 10 different subunits.(Kelman et al., 1995) It is the most processive of the DNA polymerases and is capable of replicating DNA at a rate of 1000 nucleotides per second.

DNA polymerase III is composed of two parts: a core and a holoenzyme. The core is the portion of the enzyme that contains the polymerase activity. The holoenzyme is the portion of the enzyme that contains the proofreading activity.

Structure: DNA polymerase III holoenzyme is a large complex composed of 10 different subunits, α, β, γ, δ, ε, θ, ι, χ, ψ, and τ. The core is composed of the subunits α, ε, and θ. DNA polymerase III holo

Cited: https://www.annualreviews.org/doi/10.1146/annurev.bi.57.0701... https://www.annualreviews.org/doi/10.1146/annurev.bi.64.0701...



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