I did this myself at home when my IBS was getting out of control. My girlfriend at the time, now - unsurprisingly - wife, was the donor.

I took a specific antibiotic to wipe out what I could and then we did the transplant. It helped significantly and pretty much instantaneously, though over the years I’ve regressed a bit.

I took antibiotics for acne as a teen for years, so it’s no surprise that when I stopped those I started having issues.