I don't know what "the human factor" is. Or maybe I should say, I don't think there is a single "human factor". Humans in a first world, upper middle class neighborhood coffeeshop behave very differently than humans in 1994 Rwanda, or the humans in the Stanford Prison Experiment. It's not that the humans themselves are different (or started out different), it's that the environment in one place encourages a different sort of behavior than the environment in another place. (I guess you could say I tend to favor Situationism over Dispositionism)
So, as a corollary, ideally you'd design the environment so that humans adapt to it in a particular way, thus getting rid of the 'human factor', whatever it is.
Well, getting rid of the sides of that human factor that we collectively wish to suppress. You can do it algorithmically with things like karma systems, but it's really nothing new, it's just a higher-tech way of doing what Hammurabi (and others before him) did.