I guews if you were blindly trying to breed the most durable individual specimems. But humams have major adaptatioms aside from immunity. We have cooperation and the ability to help each other. Is it worth it to let the town butcher or carpenter keel over to secure a small increase in generarional immunity?

Native Americams had no choice but to go the route of inherited immunity when they began contracting Eurasian diseases. Was it worth living through a literal apocalypse to gain immunity?